Startup Funding News, Nov. 5, 2026: 20 Startups Raise Nearly $780 Million

Thursday’s deal flow ran from electric trucks and cancer drugs to insurance AI and space debris. Twenty startups announced a combined total of nearly $780 million on November 5, 2026, led by Harbinger’s $240 million Series D. Below is who raised, who wrote the checks and what the money is for, ranked by deal size. Rounds reported in euros or yen have been converted to U.S. dollars.

1. Harbinger — $240 Million Series D

Garden Grove, Calif.-based Harbinger, which builds medium-duty electric vehicle platforms along with battery, drivetrain and autonomy systems, closed a $240 million Series D co-led by Tiger Global, Capricorn’s Technology Impact Fund and Ridgeline. Fidelity and Squarepoint came in as crossover investors, and FedEx and THOR Industries returned as strategic backers. CEO John Harris says the money will fund a push into energy storage, power generation, autonomy software and defense, and will help ramp up manufacturing. Harbinger has now raised more than $650 million since it was founded in 2021.

Source: PR Newswire — “Harbinger Raises $240 Million Series D Funding Round, Led by Tiger Global”

2. T-Therapeutics — $133 Million Series B

Cambridge, U.K.-based T-Therapeutics develops T cell receptor bispecifics aimed at intracellular targets that antibodies can’t reach. Its oversubscribed round was co-led by Advent Life Sciences and British Business Bank. Johnson & Johnson Innovation (JJDC), Eli Lilly, Samsara BioCapital and M-Ventures joined as new investors, alongside Sofinnova Partners, F-Prime, Sanofi Ventures and Tencent. The capital takes its two lead programs, one in solid tumors and one in autoimmune disease, into the clinic for proof-of-concept data.

Source: BioSpace — “T-Therapeutics announces oversubscribed $133 million Series B financing to achieve clinical proof-of-concept for first-in-class TCR bispecific therapies in cancer and autoimmune disease”

3. Alethio Therapeutics — $90 Million Series A

University of Oxford spinout Alethio Therapeutics raised an oversubscribed $90 million (£67 million) Series A, co-led by Sofinnova Partners and RA Capital with founding investor Oxford Science Enterprises. The company targets myeloproliferative neoplasms, a group of chronic blood cancers. The round funds Phase 1/2a trials of its lead antibody, ATX-011, in essential thrombocythemia. CEO Rohit Batta leads the company.

Source: BioSpace — “Alethio Therapeutics Raises $90 Million (£67 Million) in Oversubscribed Series A Financing to Advance a New Generation of Therapies for Myeloproliferative Neoplasms”

4. Kalepa — $75 Million Series B

New York-based Kalepa makes AI software that insurers, MGAs and reinsurers use for underwriting, pricing and portfolio decisions. Five years after its Series A, it raised $75 million at a $470 million valuation. Updata Partners led the round, and IA Ventures and Inspired Capital returned. The company plans to broaden its AI agent products, enter new markets and double its headcount by 2027.

Source: Tech Funding News — “Five years after its Series A, insurance AI startup Kalepa raises $75M at $470M valuation”

5. Humble Robotics — $51 Million Series A

Humble Robotics builds the Humble Hauler, a driverless electric freight truck with no cab. The San Francisco company raised a $51 million Series A led by Obvious Ventures, with Eclipse and Energy Impact Partners returning, for $75 million in total funding less than a year after its founding. The money pays for customer pilots on port drayage and warehouse routes, testing and early manufacturing.

Source: FreightWaves — “Humble Robotics raises $51M for cabless hauler pilots”

6. VÆRIDION — $33.7 Million Series A2

Munich-based VÆRIDION raised €30 million (about $33.7 million) to build the first certification-conforming prototype of its Microliner, a nine-passenger all-electric regional aircraft. SHIFT Invest and Invest-NL co-led the round, and World Fund, Project A and Vsquared Ventures returned. The company was also selected for a €94.5 million EU Innovation Fund grant, holds conditional orders for more than 130 aircraft and is targeting EASA certification in 2030.

Source: AIN — “Vaeridion Gets Funding to Build Electric Microliner Conforming Prototype”

7. Fact Base — $29 Million Series D

Tokyo-based Fact Base raised ¥4.5 billion (about $29 million) in a Series D led by Insight Partners, with Artemis Ventures and MPower Partners participating. Its product, Zmeen, is cloud-based drawing management for small and mid-sized factories. CEO Masataka Takeuchi plans to use the funds to expand internationally and keep building out the product.

Source: The SaaS News — “Fact Base Raises ¥4.5B Series D”

8. Nova Anchora — $23 Million

Boston-based Nova Anchora is developing NvA-021, a topical gel of recombinant collagen VII for dystrophic epidermolysis bullosa, a rare blistering skin disease. Viking Global Investors led the $23 million financing, which is partly tied to milestones. DEBRA Research, EB Research Partnership, EBMRF and Cure EB also invested. The money covers IND-enabling work, an FDA filing and a first clinical proof-of-concept study.

Source: BioSpace — “Nova Anchora Announces $23 Million Financing to Advance Topical Collagen VII Therapy for Dystrophic Epidermolysis Bullosa”

9. Numica — $21 Million

Numica buys small accounting practices from retiring owners, keeps their staff and clients, and moves the work onto its own AI software. The New York startup raised $21 million in equity and debt from Roosh X and Flashpoint, and co-founder and CEO Slava Orekoff says most of it will go toward buying more firms.

Source: Fortune — “Meet the AI company retiring your CPA so he can still see you face to face this tax season”

10. Green Voltis — $15.2 Million Series A

Stockholm-based Green Voltis uses AI to manage and trade battery storage across European power markets and has more than 1.2 GWh under contract or in operation. Lochpine Capital backed the entire €13.5 million (about $15.2 million) Series A. CEO Martin Kievit is also building out a power-to-compute business that would site AI data centers on grid-connected land in the Nordics.

Source: Global Startups Insights — “Green Voltis Raises €13.5M Series A to Expand AI-Powered Battery Storage Solutions in Europe”

11. Kabilio — $11.2 Million Seed

Barcelona-based Kabilio, which automates bookkeeping for accounting firms, raised €10 million (about $11.2 million) in a seed round led by Picus Capital and Visionaries Club, with Spain’s CDTI participating. The company has grown to nearly 500 accounting firm clients. The money funds the beta launch of an AI agent that collects invoices, reconciles accounts and follows up with clients over email and WhatsApp.

Source: Dealroom — “Kabilio raises €10M to put an AI agent inside accounting firms”

12. altM — $10.3 Million Series A

Bengaluru-based altM turns agricultural waste such as sugarcane bagasse and rice straw into specialty chemicals and biomaterials for beauty, textiles and packaging. Its $10.3 million Series A was led by Rainmatter and Mela Ventures, with Omnivore and Theia Ventures returning. Founders Apoorv Garg and Yugal Raj Jain, both former Tesla executives, are building a 1,000-tonne-per-year commercial plant due by 2028.

Source: Inc42 — “Cleantech Startup altM Raises $10.3 Mn To Scale Manufacturing”

13. Atmospheric AI — $10 Million Seed

Atmospheric AI builds digital twins of raw-material supply chains so manufacturers can model what inputs should cost and what carbon they carry. DBL Partners led the $10 million seed. CEO Roee Goldberg plans to expand beyond plastics into chemicals, paper and metals and to deepen work with the roughly 100 manufacturers already on the platform.

Source: The SaaS News — “Atmospheric AI Raises $10M Seed”

14. RadianX — $9 Million

Redwood City, Calif.-based RadianX, formerly California Perovskite Technology, makes ultra-thin perovskite solar modules that run sensors, wearables and connected devices on indoor and low light. SOSV and Twynam co-led the $9 million in venture and project financing. Manufacturer PUT is funding a dedicated automated 6 MW production line. Vivian Qu is co-founder and CEO.

Source: PR Newswire — “RadianX Secures $9 Million in Venture and Project Financing for Perovskite Photovoltaics”

15. Siggy — $6 Million Pre-Seed

New York-based Siggy uses AI to take patient histories and track progress between sessions with licensed clinicians, sharing a daily “Siggy Score” with both. The founders are Jonathan Sabbagh, a co-founder of Journey Clinical, and Edvard Engesæth, a co-founder of Nurx. Village Global led the $6 million round, with Albert Wenger, Immad Akhund and Gokul Rajaram among the backers.

Source: Crunchbase News — “Exclusive: Nurx And Journey Clinical Co-Founders Raise $6M For Mental Health Startup Siggy”

16. Cosmoserve Space — $6 Million Seed

Hyderabad-based Cosmoserve Space is building soft robotic systems to capture dead satellites and orbital debris. Japan’s Rebright Partners led the $6 million seed, with Aranya Holdings and Naandi Ventures joining and AUM Ventures and Shakti VC investing again. Founder Chiranjeevi Phanindra, a former ISRO scientist, also opened Base 1, which the company calls India’s first private debris removal facility. Commercial operations are targeted for 2028.

Source: Inc42 — “Spacetech Startup Cosmoserve Nets $6 Mn, Eyes Commercialisation By 2028”

17. Efy Finance — $5 Million Seed

Panama-based Efy Finance offers multi-currency accounts, Visa cards and USDT on- and off-ramps for cross-border payments in Latin America. Tether led the $5 million seed, with Astor Management AG and angel investors participating. CEO Andrés Tobón will use the money to build payment corridors in Colombia, Mexico, Bolivia and Central America.

Source: TechNode Global — “Panama-based Efy Finance raises $5M seed round led by Tether, to expand Latin American payments”

18. Lombard Systems — $4 Million Pre-Seed and Seed

Lombard Systems, which is based in Dubai and New York and was formerly called SemiLiquid/PCP, maintains the Delivery-versus-Lock standard. It lets institutions borrow against tokenized assets without moving them out of their existing securities accounts. Ethereal Ventures led the $4 million raise, with Alps Capital, First Commit Capital, Veris Ventures and Atka participating. The first institutional deployment is due by the end of 2026.

Source: PR Newswire — “Lombard Systems Raises $4 Million to Standardize Financing for Tokenized Assets”

19. Avanlee Care — $3.5 Million Seed

Billings, Mont.-based Avanlee Care gives Medicare Advantage plans a way to find and engage the family caregivers who manage members’ care. BEA Venture Fund led the $3.5 million seed, with Esther Dyson, Chrysalis Ventures and FairBridge VC participating, bringing total funding to $6 million. Founder and CEO Avanlee Christine plans to expand across the Medicare Advantage market.

Source: Fierce Healthcare — “Avanlee Care, platform for family caregivers, raises $3.5M, targeting Medicare Advantage plans”

20. Pay2o — $1.1 Million Seed

Tokyo-based Pay2o lets customers pay monthly tuition and membership fees straight from their bank accounts on a smartphone, with fees starting at 0.95%. XTech Ventures led the ¥170 million (about $1.1 million) seed, with Mizuho Capital and Plaid participating. The money goes toward signing larger customers, partnering with SaaS providers and hiring.

Source: The SaaS News — “Pay2o Raises ¥170M Seed”

The Takeaway

After Harbinger, life sciences took the two biggest checks of the day. The more telling pattern is AI moving into old-line professional services: Numica and Kabilio are both rebuilding the accounting firm, and Kalepa is doing the same for insurance underwriting. Not on this list is Isomorphic Labs, which Bloomberg reports is in talks to raise $5 billion at a $50 billion valuation. That deal’s terms are not final.